(S)-3-Hydroxy-gamma-butyrolactone

Name: (S)-3-Hydroxy-gamma-butyrolactone
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English Name ： (S)-3-hydroxy-gamma-butyrolactone
English Synonyms ： S-3-HYDROXY-Y-BUTYROLACTONE; S-(-)-beta-Hydroxy-gamma-Butyrolactone; S-(-)-3-Hydroxy-gamma-butyrolactone; (S)-3-Hydroxybutyrolactone; (+/-)-beta-Hydroxy-gamma-butyrolactone; S-(-)-3-hydroxy-y-butyrolactone; 3-hydroxy gamma butyrolactone; 4-hydroxydihydrofuran-2(3H)-one; (5S)-5-hydroxydihydrofuran-2(3H)-one; (4S)-4-hydroxydihydrofuran-2(3H)-one; S-(-)-3-Hydroxy-T-butyrolactone; (+/-)-3-Hydroxy-Gamma-Butyrolactone; 4-hydroxy-dihydrofuran-2(3H)-one
CAS Number ： 7331-52-4;5469-16-9
EINECS Number ： 434-990-4
Molecular Formula ： C4H6O3

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Product Description

English Name	(S)-3-hydroxy-gamma-butyrolactone
English Synonyms	S-3-HYDROXY-Y-BUTYROLACTONE; S-(-)-beta-Hydroxy-gamma-Butyrolactone; S-(-)-3-Hydroxy-gamma-butyrolactone; (S)-3-Hydroxybutyrolactone; (+/-)-beta-Hydroxy-gamma-butyrolactone; S-(-)-3-hydroxy-y-butyrolactone; 3-hydroxy gamma butyrolactone; 4-hydroxydihydrofuran-2(3H)-one; (5S)-5-hydroxydihydrofuran-2(3H)-one; (4S)-4-hydroxydihydrofuran-2(3H)-one; S-(-)-3-Hydroxy-T-butyrolactone; (+/-)-3-Hydroxy-Gamma-Butyrolactone; 4-hydroxy-dihydrofuran-2(3H)-one
CAS Number	7331-52-4;5469-16-9
EINECS Number	434-990-4
Molecular Formula	C4H6O3
Molecular Weight	102.0886
InChI	InChI=1/C4H6O3/c5-3-1-4(6)7-2/h3,5H,1-2H2/t3-/m0/s1
Molecular Structure
Density	1.393g/cm³
Boiling Point	1.24
Boiling Point Condition	310.3°C at 760 mmHg
Flash Point	157°C
Vapor Pressure	5.42E-05mmHg at 25°C
Physical and Chemical Properties	(S)-3-hydroxy-γ-butyrolactone is a colorless liquid, soluble in water, alcohols and other organic solvents, insoluble in petroleum ether, etc. It is a very important organic synthesis intermediate and also a very important chiral source (Chiral Pool). It is mainly used as an intermediate for regulating (R)-γ-hydroxy-β-quinolinic acid [(R)-GABOB]. (R)-GABOB is used to treat high blood lipids; (S)-Oxiracetam is a promoter of brain metabolism, and its synthesis is also derived from it; when reduced, (s)-3-hydroxy-4-aminobutyric acid can be obtained, the latter is an important intermediate for anti-AIDS drugs; the synthesized (s)-3-hydroxy-4-aminobutyric acid is a potential anticonvulsant; converting it into (s)-5-aminomethyl-1,3-oxazole-2-thione can obtain the latest - generation antibacterial drugs; in addition, (s)-N-methyl-3-hydroxyproline and (R)-N-methyl-3-methylproline also have important physiological activities, and can be obtained by simple conversion from (s)-3-hydroxy-γ-butyrolactone. Many natural products can also be synthesized from (s)-3-hydroxy-γ-butyrolactone.
Hazardous Sign	[Hazardous sign image]
Hazardous Mark	Xi: Irritant;
Risk Phrases	R36/37/38;
Safety Phrases	S26; S37/39;