(S)-3-Hydroxy-gamma-butyrolactone

(S)-3-Hydroxy-gamma-butyrolactone

English Name : (S)-3-Hydroxy-gamma-butyrolactone
English Synonyms : S-3-Hydroxy-γ-butyrolactone; (S)-(-)-3-Hydroxy-γ-butyrolactone; (S)-3-Hydroxybutyrolactone; (±)-β-Hydroxy-γ-butyrolactone; (4S)-4-hydroxydihydrofuran-2(3H)-one; 4-hydroxy-dihydrofuran-2(3H)-one; [10 additional aliases condensed]
CAS Number : 7331-52-4; 5469-16-9
EINECS Number : 434-990-4
Molecular Formula : C₄H₆O₃
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Product Description

English Name(S)-3-Hydroxy-gamma-butyrolactone
English SynonymsS-3-Hydroxy-γ-butyrolactone; (S)-(-)-3-Hydroxy-γ-butyrolactone; (S)-3-Hydroxybutyrolactone; (±)-β-Hydroxy-γ-butyrolactone; (4S)-4-hydroxydihydrofuran-2(3H)-one; 4-hydroxy-dihydrofuran-2(3H)-one; [10 additional aliases condensed]
CAS Number7331-52-4; 5469-16-9
EINECS Number434-990-4
Molecular FormulaC₄H₆O₃
Molecular Weight102.0886 g/mol
InChIInChI=1/C4H6O3/c5-3-1-4(6)7-2-3/h3,5H,1-2H2/t3-/m0/s1
Molecular Structure

(S)-3-羟基-gamma-丁内酯

Density1.393 g/cm³
Melting Point1.24°C (Refractive index note) **
Boiling Point310.3°C at 760 mmHg
Flash Point157°C
Vapor Pressure5.42 × 10⁻⁵ mmHg at 25°C
Physicochemical Properties• Appearance: Colorless liquid
• Solubility: Soluble in water, alcohols, organic solvents; insoluble in petroleum ether
• Chiral source: Important chiral pool intermediate
Applications• Synthetic intermediate for:
- (R)-GABOB (hyperlipidemia treatment)
- (S)-Oxiracetam (brain metabolism promoter)
- HIV/AIDS drug intermediates
- Antibacterial agents
- Sedatives
- Natural product synthesis
Hazard Symbol

(S)-3-羟基-gamma-丁内酯i

Xi: Irritant

Risk PhrasesR36/37/38: Irritating to eyes, respiratory system and skin
Safety PhrasesS26: In case of contact with eyes, rinse immediately
S37/39: Wear suitable gloves and eye/face protection
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