The Role of 2-Bromo-3-methylpropiophenone in Pharmaceutical Synthesis

2-Bromo-3-methylpropiophenone (CAS 1451-82-7) is a specialized organic compound widely used as a key intermediate in the synthesis of active pharmaceutical ingredients (APIs). Its unique molecular structure, featuring a bromine substituent and methyl group, makes it highly reactive in controlled reactions, enabling the production of complex drug molecules.

Key Pharmaceutical Applications

This compound serves critical functions in multiple drug development pathways:

• Antipsychotic medications: Intermediate for dopamine receptor modulators
• Cardiovascular drugs: Building block for beta-blocker synthesis
• Analgesics: Precursor in opioid alternative development
• Anti-inflammatory agents: Key component in COX-2 inhibitor production

Technical Advantages in API Manufacturing

Quality Standards in Production

Pharmaceutical-grade 2-Bromo-3-methylpropiophenone must meet stringent requirements:

• Minimum 99% purity (HPLC)
• Heavy metal content <10ppm
• Residual solvent levels meeting ICH Q3C guidelines
• Full traceability and cGMP compliance

Industry Trends and Future Outlook

The global demand for 2-Bromo-3-methylpropiophenone is projected to grow at 6.8% CAGR through 2030, driven by:

• Increasing development of CNS-targeting therapeutics
• Expansion of generic drug markets
• Advancements in continuous flow chemistry

Selecting a Reliable Supplier

When sourcing this critical intermediate, consider:

• Technical documentation completeness
• Regulatory compliance history
• Custom synthesis capabilities
• Supply chain transparency

Our pharmaceutical intermediates division offers GMP-compliant 2-Bromo-3-methylpropiophenone with full analytical documentation and batch-to-batch consistency. Contact our technical team for specification sheets and custom synthesis inquiries.